Job Description

Ihre Aufgaben



Isolation, differentiation, and design of iPS-derived immune cells. Tumor-immune co-culture systems, phagocytosis assays, and T cell killing assays. Advanced cell culture, Incucyte live-cell imaging, multicolor flow cytometry, cell sorting, immune fluorescence, ELISA, and related immunological methods. Accurate data recording, documentation using Dotmatics, and maintaining organized experimental records. Development and implementation of Standard Operating Procedures (SOPs) for reproducibility and compliance. Presentation of findings at national/international meetings and preparation of manuscripts. Supervision and training of graduate students, technicians, and lab members.

Ihre Qualifikationen



PhD in tumor biology (required). Substantial experience in the pharmaceutical or biotech industry. Proficiency in multicolor flow cytometry, cell sorting, molecular and cellular biology techniques. Hands-on expertise with iPS-derived immune models (preferred). Experience with Incucyte live-cell imaging, Dotmatics documentation platforms, and SOP writing (highly desirable).

Wir bieten



a dynamic and collaborative research environment within an international and interdisciplinary team exposure to a comprehensive range of molecular and cell biology techniques Opportunities to contribute to clinical-translational research studies

Einleitungstext



Dr. Shiv K. Singh’s laboratory is seeking a highly qualified Senior Research Associate to join our collaborative team investigating the interaction between macrophages, T cells, and tumor cells in the tumor microenvironment, with a focus on pancreatic cancer under chemo naïve and (neo)-adjuvant therapy settings.

The successful candidate will employ a wide range of functional approaches to analyze immune cell properties in animal models and patient specimens following chemo-immunotherapy and radiotherapy. This work aims to translate findings for diagnostic purposes, including biomarker identification, by analyzing samples from patients with human pancreatic cancer.