Section Biomedical Imaging, Dept. for Radiology and Neuroradiology, UKSH and Kiel University
Project description
Several hyperpolarization techniques were developed to enhance the intrinsic low signal of Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) to observe real-time and in vivo metabolic processes. Parahydrogen (pH2) is the nuclear spin isomer of molecular hydrogen that can be generated on a large scale by cooling down normal hydrogen. pH2-induced hyperpolarization (PHIP) already demonstrated 13C-polarization of pyruvate above 10%. Within the scope of this R&D project, a novel parahydrogen-induced polarizer will be constructed. The project continues our preliminary studies (Ellerman et al., Nat. Comm. 2023, DOI: 10.1038/s41467-023-40539-9) and our recent unpublished know-how.
Start in our team:
This Ph.D. position (or 70% Post.Doc.) aims to develop a novel high-pressure PHIP-reactor with applications in biology and medicine. We are looking for professional and competent support to start
as soon as possible
,
limited
for 3 years.
What we offer:
The salary will be based on the German E13 TV-L scale, if terms and conditions under collective bargaining law are fulfilled
Part-time employment currently 28,75 hours/week
A position at the second-largest University Hospital in Germany with access to state-of-the-art magnetic resonance equipment
Access to imaging, chemical, and RF-electronics facilities of the section of biomedical imaging of Kiel University (PI Prof. Jan-Bernd Hövener)
An intensive Ph.D. supervision in an interdisciplinary team
Your tasks:
Developing the PHIP-hyperpolarizer
Performing hyperpolarization experiments with PHIP-hyperpolarizer
Presenting the results at national and international conferences and publishing results in scientific journals
Your profile:
You have completed your university studies (master’s degree or German Diploma) in physics, chemical physics, biomedical technology, or a comparable engineering field
Knowledge in NMR/MRI are not prerequisite
You have knowledge, practical experience in automation, hardware construction
Experience in programming, modeling, and analyzing data would be an advantage
You have a very good command of spoken and written English
Please submit your application until
25th November 2025
, indicating the reference number
27463
.
PI of the project and contact person:
Dr. Andrey Pravdivtsev, andrey.pravdivtsev@rad.uni-kiel.de
BMBF hyperpolarization group leader
Campus Kiel
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Veröffentlicht am: 11.11.2025
Standort:
Kiel, Schleswig-Holstein, DE, 24105
Ausschreibungsnummer: 27463
Haben Sie Fragen?
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Ihr Kontakt zu uns: Habil., Ph.D. Andrey Pravdivtsev #0431 880-5855
Recruiter: Jessica Puton # 0431 - 500 11191 # https://rmkcdn.
Benefits am UKSH
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