The Hannover Medical School (MHH), with about 10.000 employees the biggest company of Lower Saxony, is a university institution for research and teaching in the human and dental medicine and a university hospital of supra-maximum medical care. Research, teaching, medical care and administration work hand in hand in the integration model at the MHH-campus.
At TWINCORE, Centre for Experimental and Clinical Infection Research, clinician scientists and basic researchers from various disciplines conduct infection research side by side. Our focus is on translational research at the interface between basic research and clinical development. Beyond neutralization, antibodies can elicit an armory of additional Fc dependent innate effector functions. Emerging data points to the importance of these effector functions for antibody mediated control of viral infections like HIV, SARS-CoV-2 or RSV. One major goal of our group "Anti-Viral Antibody-omics" at the Institute for Experimental Infection Research is to characterize protective antibody responses in humans. Furthermore, we aim to develop novel, improved antibody based anti-viral therapies.
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