Dc9: Engineering Designer Fluorinases

Stuttgart, BW, DE, Germany

Job Description

ORGANISATION




The

University of Stuttgart

represents an outstanding, world-renowned research and first class teaching in one of Europe's most dynamic industrial regions. As a reliable employer, the university supports and promotes the academic careers of its researchers. It is proud of its employees, who currently come from over 100 different countries. The university is a partner for knowledge and technology transfer and focuses on multidisciplinarity.


The position we offer will be embedded in the Department of Technical Biochemistry at the Faculty of Chemistry (https://www.f03.uni-stuttgart.de/en/). The Faculty of Chemistry at the University of Stuttgart hosts over 250 scientists, including 24 professors, and more than 900 students across chemistry and materials science. Its research is supported by collaborations with Max Planck, Frauenhofer, and other research institutes. The department emphasizes real-world applications, such as energy, catalysis, synthetic biology, and adaptive materials. Prof. Dr. Hajo Kries is head of the Department of Technical Biochemistry (https://www.ibc.uni-stuttgart.de/en/tbc/), which works at the interface of biocatalysis and natural product biosynthesis and focuses on transforming enzymes into powerful catalysts for sustainable chemistry. We value collaboration, creativity, and mutual respect – science is our passion, and we support each other.


ROLES AND RESPONSIBILITIES




The main part of your PhD research (4 years in total) will be carried out at the

University of Stuttgart

(Germany) under the supervision of

Prof. Dr. Hajo Kries

in the Department of Technical Biochemistry at the Faculty of Chemistry. Within these four years, an academic research stay (of 12 months) will take place at the

University of Groningen

(Netherlands) under the supervision of

Prof. Dr. Clemens Mayer

. Additionally, an industrial secondment at the company

BASF

(Germany) is foreseen. The Horizon Europe Marie Sk?odowska-Curie Actions (MSCA) – Doctoral Network (DN) project starts in January 2026. The date of recruitment and start of the PhD project is planned for April 2026 and latest in December 2026. Your

PhD degree

(so-called double degree) will be awarded based on successful completion of the research work from

two universities (University of Stuttgart and University of Groningen)

. You will also be required to participate in the training events and workshops organized by the DN- Joint Doctorates (JD) program. As a MSCA fellow, you are also expected to

contribute your time in the dissemination of your PhD project's result

through public engagement and other scientific platforms.


The PhD research will focus on





Design and engineering of new-to-nature enzymes Cloning genes, expression and purification of proteins Directed evolution experiments Characterization of enzyme function and activity Chemical synthesis of ligands, substrates, and standards (academic secondment) Application of computational tools for enzyme design Transfer of fluorinase reaction to industrial setting (industrial secondment)

Primary supervisor:

Prof. Dr. Hajo Kries


Secondary supervisor:

Prof. Dr. Clemens Mayer


Recruiting institution:

University of Stuttgart (Germany)


Double degree awarding institution:

University of Groningen (the Netherlands)


QUALIFICATIONS





An outstanding M.Sc. degree in Chemistry, Chemical Biology, Biochemistry, or a related field Eligible as a graduate student at the University of Stuttgart (Germany) and the University of Groningen (the Netherlands) Research experience in enzyme purification and assays, organic chemistry, analytical methods (HPLC, GC, MS, NMR etc.) Experience in molecular molecular cloning or computational protein design is a plus Ability to work in an international and interdisciplinary team High motivation An integrative and cooperative personality with excellent communication and social skills Fluency in English – written and oral

CONDITIONS OF EMPLOYMENT





We offer you:



a salary according to the German public sector pay scale TV-L E13 (100%), commensurate with experience and qualifications, comprehensive social security coverage according to German standards, including health, unemployment, and pension insurance, and statutory accident insurance for workplace accidents, 30 days of paid annual leave, a PhD training programme and enrolment in the Graduate Academy of the University of Stuttgart (GRADUS).

The position is a full-time appointment (TV-L E13, 100%) for a total duration of four years. The preferred starting date is between April 1st and July 1st 2026.


The conditions of employment: https://www.uni-stuttgart.de/en/university/employer/.



APPLICATION PROCEDURE





To apply for the position, kindly provide:


A letter of motivation including a statement of your research interests, relevant skills and experience and an explanation for the choice of position(s); A CV including publication list (if applicable); Names and contact details of up to three referees willing to write confidential letters of recommendation; Copies of relevant diplomas including explanation of international grades.

Please upload applications only according to instructions at

https://haloverse.eu/recruitme... (https://haloverse.eu/recruitment/)


Address applications to:

Prof.

Dr. Hajo Kries




At the University of Stuttgart, we actively promote diversity among our employees. We have set ourselves the goal of recruiting more women scientists and employing more people with an international background, as well as people with disabilities. We are therefore particularly pleased to receive applications from such people. Regardless, we welcome any good application. Women who apply will be given preferential consideration in areas in which they are underrepresented, provided they have the same aptitude, qualifications and professional performance. Severely disabled applicants with equal qualifications will be given priority.


As a certified family-friendly university, we support the compatibility of work and family, and of professional and private life in general, through various flexible modules. We have an employee health management system that has won several awards and offers our employees a wide range of continuing education programs. We are consistently improving our accessibility. Our Welcome Center helps international scientists get started in Stuttgart. We support partners of new professors and managers with a dual-career program.


Unsolicited marketing is not appreciated.


APPLICATION DEADLINE




You may apply until 31st of December 2025 11:59pm / before 1st of January 2026 Central European Time (CET) for this position by means of the online application form (click on 'Apply' below on the advertisement on the HaloVerse website).

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Job Detail

  • Job Id
    JD3748036
  • Industry
    Not mentioned
  • Total Positions
    1
  • Job Type:
    Vollzeit
  • Salary:
    Not mentioned
  • Employment Status
    Permanent
  • Job Location
    Stuttgart, BW, DE, Germany
  • Education
    Not mentioned