Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. – Hans-Knöll-Institut (HKI)
for four years. Project title: Deciphering microbiome enteric nervous system interactions in sepsis # Research Area: Sepsis is a life threatening syndrome driven by a dysregulated host response to infection, and a major cause of mortality worldwide. The gut microbiome…
for four years. Project title: My enemy’s enemy is my friend – Mycoparasites as unexplored resource for antiinfectives # Research Area: Early diverging fungi (EDF) represent an untapped resource in natural product research. EDF of the mycoparasitic order Dimargaritales infect…
for four years. Project title: Scalable moss bacteria co cultivations for the discovery and production of antimicrobials # Research Area: Natural products serve as the predominant starting point for the development of novel antimicrobials, which are urgently needed to fight…
for four years. Project title: Liver on chip based elucidation of macrophage drug interactions in invasive candidiasis # Research Area: Invasive candidiasis is a devastating disease of immunocompromised patients associated with a high mortality and challenging antifungal management. Despite extensive…
for four years. Project title: A novel role of human p11 dependent EGFR in regulating phagosome maturation and antifungal defence # Research Area: The ability of pathogens to evade phagosomal killing is critical for their pathogenicity. Previously, we have identified…
for four years. Project title: Advancing image quantification of organ on chip based experiments within JIPipe # Research Area: During recent years, the research unit Applied Systems Biology (ASB) at the Leibniz HKI has developed an entirely new approach towards…
for four years. Project title: Candida albicans lipases as microbiome modulators # Research Area: Fungi are an integral part of the human microbiome, and they interact with the host and the bacterial community members in a myriad of ways. Candida…
for four years. Project title: Extracellular vesicles as a key defense mechanism against Aspergillus fumigatus # Research Area: Aspergillus fumigatus is the most common airborne fungal pathogen. Inhaled spores encounter various host cells in the lung, with neutrophils playing a…
for four years. Project title: Investigation of RNA modification by natural products across species # Research Area: Fungi are a growing threat to our society, currently causing over a billion human infections and 3.75 million deaths annually (gaffi.org). Rising rates…
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The position is initially limited to three years. # Research Area: Members of the genus Fusarium are some of the few trans kingdom fungal pathogens, being able to infect plants, and at the same time, cause severe superficial and invasive…
DieForschungsgruppe Mikrobielle Immunologie erforscht die Interaktionen zwischen dem Pilz Candida und dem Wirt um besser zu verstehen, welche Wechselwirkungen zwischen Wirt und Pilz zu pathophysiologischen Veränderungen führen und wie diese Veränderungen zur Entstehung schwerwiegender Erkrankungen beitragen. Zur Untersuchung dieser Fragestellungen…
in Vollzeit für zunächst zwei Jahre, mit der Möglichkeit der Verlängerung. Wir wünschen uns eine kreative Persönlichkeit, die mit viel Tatkraft die Forschungsergebnisse und anderen wichtigen Ereignisse unseres Instituts und seiner großen Forschungsvorhaben für eine zielgruppenorientiert aufbereitet und kommuniziert. Sie…
W3 Professorship for Microbial Pathogenicity We are looking for a researcher (f/m/d) with extensive expertise in the study of severe fungal infections of humans, in particular caused by yeast species, for example of the genus Candida, who will significantly shape…
Research area: Natural products, especially of bacterial origin, are an important source of new antibiotics. These metabolites further play significant roles in microbial interactions and communication. For the discovery of novel bioactive natural products, we are investigating interactions in the…