Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C) at Forschungszentrum Jülich houses some of the world`s most advanced electron microscopes and tools for nanocharacterisation. Under one roof, the scientific research combines current issues in cryo-EM on biomacromolecules and in condensed matter physics with the aim of advancing electron microscopy methods. The facility has been extended with state-of-the-art cryo-microscopes ThermoFisher 2 x Titan Krios, Talos Arctica and Talos 120 as well as FIB-SEM Aquilos 2 and Arctis. In the framework of ER-C2.0, we expanded our instrumentation with worldwide unique nanocharacterisation tools for the Life and the Physical Sciences. In addition to routine single-particle cryo-EM and in situ cryo-electron tomography, emerging 4D-STEM, helium temperature and Cc-corrector technologies are actively developed in a new building. The Structural Biology subinstitute (ER-C-3) investigates the structural and molecular mechanism of membrane biology processes and advances the development of cryo-EM related methodology.
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