Job Description

03.12.2025 | Tyler
We are seeking a Student Assistant (HiWi) to join the lab of Dr. Michael Tyler at the Georg-Speyer-Haus, supporting our research using data integration approaches to study cancer progression.


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Description

Our lab aims to understand the phenotypes of different tumour cells and the interactions between them, and to measure how these change during the progression from healthy tissue to advanced metastatic disease. Our work is centered around the curation and integration of many published genomic datasets, with a focus on single-cell RNA-sequencing (scRNA-seq) and spatial transcriptomic data. By conducting large-scale comparisons across many patients, cancer types and disease stages, we aim to uncover general principles of tumour development and identify new therapeutic opportunities. This work involves analysis of large datasets with statistical computing tools. Your tasks will include curating datasets and assisting in the development of computational methods for detection and comparison of cell states and interactions. Specific challenges include efficient handling of large volumes of data, and controlling for technical artefacts while preserving biological effects. Read more about Michael Tyler’s research on our website.

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Requirements

Experience with programming (ideally R or Python) An interest in cancer research and computational biology Self-motivation and a cooperative nature Proficiency in written and spoken English Candidates must be currently enrolled at a university in Germany, studying life sciences or a numerical discipline
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We offer

Excellent mentorship and development of a scientific profile An outstanding international cancer research environment A collaborative and friendly atmosphere Flexible working hours A 6-month contract with the option for extension
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Interested?

Applications should be submitted electronically to bewerbung@georg-speyer-haus.de as a single PDF containing a cover letter, a CV and the names and contact details of two referees. For further information, please contact Dr. Michael Tyler (m.tyler@georg-speyer-haus.de).



Our international working environment promotes equal opportunities for all staff regardless of gender, age, cultural background, nationality or impairments under criteria of scientific excellence. Applications from women are explicitly welcome. Disabled individuals will be preferred in case of equal qualification.