Job Description

Job Id: 11042

Fixed-term of 3 years | Part-time with 65% | Salary according to TV-L E13

We are UKM.

We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.





To meet our high standards every day, we are looking forward to your scientific expertise –

ideally with you on board!

THE GROUP:

The Emmy Noether-funded research group of Dr. Dr. med. Alexander Busch investigates the regulation of the hypothalamic-pituitary-gonadal (HPG) axis—a key system in human reproductive development and fertility. The group combines clinical cohorts, population-scale genetics, and molecular biology to understand how early life periods, such as minipuberty and puberty, shape reproductive capacity.





The position is embedded in the IMF-funded project “ANDROGEN”, which aims to functionally validate newly identified genetic variants that regulate quantitative spermatogenesis. This integrative project combines GWAS, bulk and single-cell transcriptomics, protein validation, and regulatory reporter assays.





Learn more about the group here.

YOUR MISSION:

Investigate how genetic variants affect male reproductive function Perform single-nucleus and bulk RNA sequencing of testicular tissue Validate gene expression at the protein level via IHC and Western blotting Analyze large-scale transcriptomic data (R, Python) Test allele-specific regulatory activity using luciferase reporter assays Integrate omics data to identify functional variants affecting spermatogenesis

REQUIREMENTS:

A Master’s degree in Biology, Molecular Medicine, Biochemistry, Biotechnology, or a related discipline Solid wet-lab experience in molecular biology, ideally with tissue or protein work Motivation to develop bioinformatics and data analysis skills (training provided) Proficiency in English (spoken and written); German is a plus but not required Team spirit, communication skills, and scientific curiosity Prior experience with transcriptomics and/or reproductive biology

WE OFFER:

A full 3-year PhD position within a dynamic Emmy Noether group A central role in a cutting-edge multi-omics project with direct translational relevance Individual mentoring, conference participation, and career development support A collaborative, international, and family-friendly work environment




For inquiries, please contact: Dr. Dr. med. Alexander S. Busch, alexandersiegfried.busch@ukmuenster.de

Apply now via our career portal until 27.08.2025 including:

A motivation letter describing your interest in reproductive biology and genomics A brief summary of your laboratory and/or analytical experience Your CV Names and contact details of 1–2 referees willing to provide a letter of reference

BENEFITS:

Exciting projects


Further education and training


Interdisciplinary collaboration


Be part of the research innovation


Even more benefits


(*gn=gender neutral)


More Information


Questions about how to apply? Click here



Applications of women are specifically invited. In the case of similar qualifications, competence, and specific achievements, women will be considered on preferential terms within the framework of the legal possibilities. Handicapped candidates with equivalent qualifications will be given preference. Due to legal requirements working with us is only permitted with complete vaccination against measles.



Universitätsklinikum Münster


Albert-Schweitzer-Campus 1 | 48149 Münster | www.ukm.de