Job Description

Ihre Aufgaben



Highly viewed by the German Research Foundation (DFG), this project is a part of a large collaborative research center “Quantitative Synaptology” (SFB1286), and focuses on investigation of the regulatory role of the synaptic vesicle cluster. The synaptic vesicle cluster is a key component of the presynaptic boutons, whose function is not limited to storage and release of neurotransmitter. Our previous data indicate that the synaptic vesicle cluster can be seen as a master organizer, regulating the architecture, dynamics, and function of synapses. This project aims to dissect individual aspects of this regulation, by investigating the behavior and effects of the synaptic vesicle cluster in cellular context outside of the confines of a synapse, including in non-neuronal cells. In the course of this project, the student will acquire proficiencies in basic and advanced lab techniques, including but not limited to super resolution fluorescence microscopy and live imaging, work with primary and iPSC-derived neuronal cultures, organelle transfer, immunocytochemistry and others.



Ihre Qualifikationen



Master’s degree (or equivalent) in Life Sciences with a strong academic record Interest in Cell Biology and Neuroscience Experience in wet lab work High level of motivation and initiative, strong academic research orientation Communication and teamwork skills Fluent written and spoken English Data analysis and programming skills are an advantage

Wir bieten



Structured PhD training through the Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GAUSS / GGNB) Payment and benefits based on the German Public Service Payscale (TV-L) guidelines Highly international and interdisciplinary team Well-equipped laboratory, including state-of-the-art imaging facility National and international collaborations Organized networking events Personalized supervision and support in further training

Einleitungstext



The Institute for Neuro and Sensory Physiology, University Medical Center Göttingen (UMG), Göttingen, Germany offers a position as PhD Student (m/f/x).

The successful candidate will join a research group led by Dr. Sofiia Reshetniak working on the mechanisms regulating synaptic architecture.